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Eli Lilly (LLY) Announces Positive Phase 3b Results for Taltz and Zepbound Combination Treatment in Psoriasis and Obesity
Eli Lilly announced positive Phase 3b results for the combination treatment of Taltz (ixekizumab) and Zepbound (tirzepatide) for adults with moderate-to-severe plaque psoriasis and obesity. The study showed that 27.1% of participants achieved both complete skin clearance and at least 10% weight loss with the combination, significantly outperforming Taltz alone. This marks Taltz as the first psoriatic biologic to successfully address psoriasis in conjunction with obesity using an incretin therapy, suggesting that treating obesity can improve psoriasis outcomes.