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Prothena Q4 Earnings Meet Estimates, Pipeline Progress in Focus
Prothena (PRTA) reported a Q4 2025 adjusted loss per share of 45 cents, meeting estimates, but revenues of $0.02 million missed the Zacks Consensus Estimate. Despite a 42% decline in share price over the past year, the company presented a positive outlook for 2026, expecting up to $105 million in clinical milestone payments from collaborations with Bristol Myers Squibb and Novo Nordisk. Prothena’s pipeline continues to advance with key programs for Parkinson’s disease, ATTR amyloidosis, and Alzheimer’s disease progressing through late-stage trials.