Revolution Medicines Conference: CEO Details Daraxonrasib Phase III Timeline, First-Line PDAC Push

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Revolution Medicines CEO Mark Goldsmith outlined the company’s plans for daraxonrasib, including the Phase III RASolute 302 trial in second-line pancreatic cancer, with top-line data expected in 1H 2026. The company is also expanding into first-line metastatic PDAC with the RASolute 303 trial and advancing two Phase III programs for zoldonrasib. Additionally, Revolution Medicines plans a first-in-human trial for RM-055 by year-end and is pursuing a global commercialization build.

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